Hairy Cell Leukemia Foundation 2023 CONFERENCE

Medical and Scientific Sessions

CONFERENCE DAY ONE - THURSDAY, OCTOBER 12, 2023

Location: Jefferies, 100 Bishopsgate, London

All listed times are in the United Kingdom/London time.

8:45 am to 9:30 am

Continental Breakfast and Networking

9:30 am to 9:45 am eastern

Opening Remarks from HCLF Leadership

9:45 am to 10:30 am

Research Presentation and Q&A (Zoom)

  • Dr. Thorsten Zenz, University Hospital Zürich

  • “Charting the Surfaceome to Eliminate Hairy Cell Leukemia”

Dr. Zenz is a current HCL2025 grantee.

10:30 am to 11:15 am

Research Presentation and Q&A (Zoom)

  • Dr. David Ritchie, Melbourne Health, Royal Melbourne Hospital-City Campus

  • “Integration of Molecular and Immunology Signals for Prognostication in HCL”

Dr. Ritchie is a current HCL2025 grantee.

11:15 am to 11:30 am

Break

11:30 am to 12:00 pm

Working Group: Updating the HCL Consensus Guidelines

Focus: Initial Treatment

Facilitator: Dr. Robert Kreitman, NIH

12:00 pm to 12:30 pm

Working Group: Updating the HCL Consensus Guidelines

Focus: Treatment at Relapse

Facilitator: Dr. Tamar Tadmor, Bnai-Zion Medical Center

12:35 pm to 1:10 pm

Lunch

1:15 pm to 2:00 pm

Research Presentation and Q&A

  • Dr. Clive Zent, University of Rochester James P. Wilmot Cancer Institute

  • “Splenic B Cell Lymphomas: Analysis of Immune Microenvironment”

Dr. Zent was a 2021/2022 HCL research grantee.

2:00 pm to 2:45 pm

Research Presentation and Q&A

  • Dr. Evgeny Arons and Dr. Chi-Ping Day, National Institutes of Health (NIH)

  • “Characterization of Hairy Cell Leukemia Variant and Unmutated IGHV4-34+ Expressing Variant by Whole Exome and Single Cell Sequencing”

Dr. Evgeny Arons is a current HCL research grantee with Dr. Robert Kreitman.

2:45 pm to 3:30 pm

Research Presentation and Q&A

  • Dr. Christopher Oakes and Kyoko Yamaguchi, The Ohio State University

  • “DNA Methylation-based Classification of Hairy Cell Leukemia and Splenic B Cell Lymphoma Reveals Novel Disease Mechanisms”

Dr. Oakes was a 2017 and 2020 HCL research grantee.

3:30 pm to 3:45 pm

Break

3:45 pm to 4:15 pm

Working Group: Updating the HCL Consensus Guidelines

Focus: HCL Variant

Facilitator: Dr. Clive Zent, University of Rochester James P. Wilmot Cancer Institute

4:15 pm to 4:45 pm

Working Group: Updating the HCL Consensus Guidelines (Zoom)

Focus: Infection prevention and treatment

Facilitator: Dr. Bernhard Wörmann, The Charité – Universitätsmedizin Berlin

4:45 pm to 5:00 pm

Wrap-up and Overview of Day Two

5:00 pm to 7:30 pm

Reception

Drinks and canapés hosted by the Hairy Cell Leukemia Foundation

Location: Paradise Green, 100 Bishopsgate, London

CONFERENCE DAY TWO - FRIDAY, OCTOBER 13, 2023

Location: Jefferies, 100 Bishopsgate, London

8:30 am to 9:00 am

Continental Breakfast

Location: Jefferies, London

9:00 am to 9:15 am

Welcome back from HCLF Leadership

9:15 am to 10:00 am

Research Presentation and Q&A

  • Dr. Jae Park, Sloan Kettering Institute for Cancer Research

  • “Chemotherapy-free Therapy for Classic HCL”

Dr. Jae Park and Dr. Omar Abdel-Wahab are current HCL2025 grantees.

10:00 am to 10:45 am

Research Presentation and Q&A

  • Dr. Enrico Tiacci, University of Perugia Institute of Hematology and Center for Hemato-Oncology Research

  • “Chemotherapy-free Strategies in Hairy Cell Leukemia”

Dr. Enrico Tiacci is a current HCL2025 grantee.

10:45 am to 11:00 am

Break

11:00 am to 11:30 am

Working Group: Updating the HCL Consensus Guidelines

Focus: Investigational Approaches

Facilitator: Dr. Enrico Tiacci, University of Perugia Institute of Hematology and Center for Hemato-Oncology Research

11:30 am to 12:15 pm

Research Presentation and Q&A

  • Dr. Marc Seifert, University Hospital Düsseldorf

  • “Exploiting Metabolic Dependencies, Tumor Plasticity and their Consequences for Drug Response of HCL”

Dr. Marc Seifert is a current HCL2025 grantee.

12:15 pm to 1:00 pm

Research Presentation and Q&A

  • Dr. Reshmi Parameswaran, Case Western Reserve University School of Medicine

  • “A Ligand-based CAR-T Therapy for HCL”

Dr. Reshmi Parameswaran is a current HCL2025 grantee.

1:00 pm to 1:30 pm

Lunch

1:30 pm to 2:15 pm

Research Presentation and Q&A (via Zoom)

  • Dr. Marco Ruella, Perelman School of Medicine at the University of Pennsylvania

  • “Precision Targeting of HCL using Chimeric Antigen Receptor T cells”

Dr. Marco Ruella is a current HCL2025 grantee.

2:15 pm to 2:45 pm

Research Presentation and Q&A (via Zoom)

  • Dr. Susan Slager, Mayo Clinic

  • “What a GWAS of HCL could provide: Modeled by CLL”


2:45 pm to 3:15 pm

Conference wrap-up, announcements, and next steps